Antibiotic resistance

We have been studying antibiotic resistance in Campylobacter jejuni, Shiga toxin-producing E. coli (STEC), Salmonella sp., and group B Streptococcus. We are also characterizing resistance mechanisms and the distribution of resistance genes in different environments.

                       

• We demonstrated that non-O157 STEC strains were more likely to be resistant than O157 STEC, and that patients with resistant infections were more likely to be hospitalized (See: Mukherjee et al. Emerg Infect Dis 2017).

                                     

• Our studies of C. jejuni from human patients have shown high rates of disease and resistance to clinically important antibiotics (See: Cha et al., Epidemiol Infect 2016; Cha et al., Frontiers Microbiol 2016).
• We also observed a high frequency of resistance in C. jejuni recovered from cattle, though the prevalence and resistance profiles varied by herd (See: Cha et al. Frontiers Microbiol 2017).